BE-18257B
Modify Date: 2024-01-04 13:59:27
BE-18257B structure
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Common Name | BE-18257B | ||
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| CAS Number | 136553-74-7 | Molecular Weight | 612.71700 | |
| Density | 1.23g/cm3 | Boiling Point | 1012.2ºC at 760 mmHg | |
| Molecular Formula | C31H44N6O7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 566ºC | |
| Name | Cyclo(-D-Glu-Ala-D-allo-Ile-Leu-D-Trp) |
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| Density | 1.23g/cm3 |
|---|---|
| Boiling Point | 1012.2ºC at 760 mmHg |
| Molecular Formula | C31H44N6O7 |
| Molecular Weight | 612.71700 |
| Flash Point | 566ºC |
| Exact Mass | 612.32700 |
| PSA | 198.59000 |
| LogP | 2.76890 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.574 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | GT9160000 |
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An endothelin receptor (ETA) antagonist isolated from Streptomyces misakiensis.
Biochem. Biophys. Res. Commun. 178 , 132, (1991) A competitive endothelin (ET) antagonist, BE-18257B, was isolated from the fermentation products of Streptomyces misakiensis. It is a novel cyclic pentapeptide, cyclo(-D-Glu-L-Ala-allo-D-Ile-L-Leu-D-T... |
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[Agonists and antagonists to endothelin receptors].
Tanpakushitsu Kakusan Koso. 38(11) , 1827-40, (1993)
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Effects of endothelin-1 and endothelin-A receptor antagonist on recovery after hypothermic cardioplegic ischemia in neonatal lamb hearts.
Circulation 92(9 Suppl) , II400-4, (1995) Prior studies suggest an important role for coronary endothelium in ischemia/reperfusion (I/R) injury. Decreased endothelial release of the vasodilator nitric oxide occurs after I/R, but the role of t... |