Vitacoxib

Modify Date: 2024-09-17 08:45:39

Vitacoxib Structure
Vitacoxib structure
Common Name Vitacoxib
CAS Number 1374128-90-1 Molecular Weight 347.819
Density 1.4±0.1 g/cm3 Boiling Point 582.1±50.0 °C at 760 mmHg
Molecular Formula C16H14ClN3O2S Melting Point N/A
MSDS N/A Flash Point 305.9±30.1 °C

 Use of Vitacoxib


A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use.

 Names

Name 2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine
Synonym More Synonyms

 Vitacoxib Biological Activity

Description A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use.
References References 1. Wang J, et al. Regul Toxicol Pharmacol. 2017 Jun;86:49-58. 2. Wang J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:270-274. View Related Products by Target Cyclooxygenase (COX)

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 582.1±50.0 °C at 760 mmHg
Molecular Formula C16H14ClN3O2S
Molecular Weight 347.819
Flash Point 305.9±30.1 °C
Exact Mass 347.049530
LogP 1.87
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.655

 Synonyms

Pyridine, 2-[4-chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)-
2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine