Panidazole

Modify Date: 2024-01-08 21:53:45

Panidazole structure	Common Name	Panidazole
	CAS Number	13752-33-5	Molecular Weight	232.23900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₂N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Panidazole

Panidazole is an amoebicide.

Name	4-[2-(2-methyl-5-nitroimidazol-1-yl)ethyl]pyridine
Synonym	More Synonyms

Description	Panidazole is an amoebicide.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
In Vitro	Panidazole in concentrations of 0.02-1 mM increases the mutation frequency of Klebsiella pneumoniae, Escherichia coli K12 and Citrobacter freundii to streptomycin resistance, including streptomycin dependence, in Luria and Delbrück's fluctuation test[1].
In Vivo	In 100 cases of vaginal trichomoniasis treated with panidazole at the dose of 1.0 g per day for seven days in half of the patients and for 10 days in the other half, we obtained 50% and 60% cure rates[3].
References	[1]. Voogd CE, et al. The mutagenic action of nitroimidazoles. II. Tinidazole, ipronidazole, panidazole and ornidazole. Mutat Res. 1977 Apr;48(2):155-61. [2]. Botero D, et al. Treatment of intestinal amoebiasis and vaginal trichomoniasis with panidazole and its comparison with metronidazole. Trans R Soc Trop Med Hyg. 1977;71(6):508-11.

Molecular Formula	C₁₁H₁₂N₄O₂
Molecular Weight	232.23900
Exact Mass	232.09600
PSA	76.53000
LogP	2.26060
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT5660000

CHEMICAL NAME :: Pyridine, 4-(2-(2-methyl-5-nitroimidazol-1-yl)ethyl)-

CAS REGISTRY NUMBER :: 13752-33-5

BEILSTEIN REFERENCE NO. :: 0533483

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C11-H12-N4-O2

MOLECULAR WEIGHT :: 232.27

WISWESSER LINE NOTATION :: T6NJ D2- AT5N CNJ B1 ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 100 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 48,155,1977

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-nitro-2-methyl-1-[2-(4-pyridinyl)-ethyl]-imidazole

Panidazole

EINECS 237-334-3

Pyridine,4-(2-(2-methyl-5-nitroimidazol-1-yl)ethyl)

Panidazolum

Panidazolum [INN-Latin]

Panidazole [INN:BAN]

Panidazol [INN-Spanish]

4-[2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl]-pyridine

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Panidazole

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