Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt

Modify Date: 2024-01-11 16:33:30

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt structure	Common Name	Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt
	CAS Number	138949-73-2	Molecular Weight	619.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₄₁N₉O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt

Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research[1][2][3][4].

Name	thr-arg-ser-ala-trp
Synonym	More Synonyms

Description	Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research[1][2][3][4].
Related Catalog	Signaling Pathways >> Others >> Others
References	[1]. Fenton AJ, et.al. A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111]. Endocrinology. 1991 Dec;129(6):3424-6. [2]. Ibáñez L, et.al. Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1. Int J Mol Sci. 2022 Aug 1;23(15):8551. [3]. Lozano D, et.al. Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation. Acta Biomater. 2010 Mar;6(3):797-803. [4]. Nácher-Juan J, et.al. Osteostatin Inhibits Collagen-Induced Arthritis by Regulation of Immune Activation, Pro-Inflammatory Cytokines, and Osteoclastogenesis. Int J Mol Sci. 2019 Aug 7;20(16):3845.

Description

Related Catalog

Signaling Pathways >> Others >> Others

References

[1]. Fenton AJ, et.al. A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111]. Endocrinology. 1991 Dec;129(6):3424-6.

[2]. Ibáñez L, et.al. Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1. Int J Mol Sci. 2022 Aug 1;23(15):8551.

[3]. Lozano D, et.al. Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation. Acta Biomater. 2010 Mar;6(3):797-803.

[4]. Nácher-Juan J, et.al. Osteostatin Inhibits Collagen-Induced Arthritis by Regulation of Immune Activation, Pro-Inflammatory Cytokines, and Osteoclastogenesis. Int J Mol Sci. 2019 Aug 7;20(16):3845.