BAN ORL 24
Modify Date: 2024-01-05 13:47:17
BAN ORL 24 structure
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Common Name | BAN ORL 24 | ||
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| CAS Number | 1401463-54-4 | Molecular Weight | 506.508 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H37Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAN ORL 24BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). IC50 value: 0.27 nMTarget: NOP receptorBAN ORL 24 inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant. |
| Name | 1-Benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]-D-prolinamide dihydrochloride |
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| Synonym | More Synonyms |
| Description | BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). IC50 value: 0.27 nMTarget: NOP receptorBAN ORL 24 inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant. |
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| Related Catalog | |
| References |
| Molecular Formula | C27H37Cl2N3O2 |
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| Molecular Weight | 506.508 |
| Exact Mass | 505.226288 |
| Storage condition | 2-8℃ |
| 2-Pyrrolidinecarboxamide, 1-(phenylmethyl)-N-(3-spiro[isobenzofuran-1(3H),4'-piperidin]-1'-ylpropyl)-, (2R)-, hydrochloride (1:2) |
| 1-Benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]-D-prolinamide dihydrochloride |
| BAN ORL 24 |