Vat-Cit-PAB-Monomethyl Dolastatin 10
Modify Date: 2024-01-10 17:41:09
Vat-Cit-PAB-Monomethyl Dolastatin 10 structure
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Common Name | Vat-Cit-PAB-Monomethyl Dolastatin 10 | ||
|---|---|---|---|---|
| CAS Number | 1415329-13-3 | Molecular Weight | 1176.512 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 1237.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C60H93N11O11S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 702.0±34.3 °C | |
Use of Vat-Cit-PAB-Monomethyl Dolastatin 10Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB. |
| Name | VAL-CIT-PAB-MMAD |
|---|---|
| Synonym | More Synonyms |
| Description | Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB. |
|---|---|
| Related Catalog | |
| Target |
Auristatin |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 1237.2±65.0 °C at 760 mmHg |
| Molecular Formula | C60H93N11O11S |
| Molecular Weight | 1176.512 |
| Flash Point | 702.0±34.3 °C |
| Exact Mass | 1175.677612 |
| LogP | 6.49 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.564 |
| L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-[(5S,8S,11S,12R)-12-[2-[(2R)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-2-oxoethyl]-4,1 0-dimethyl-5,8-bis(1-methylethyl)-11-[(1S)-1-methylpropyl]-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl]- |
| L-Valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-5,8-diisopropyl-12-(2-{(2R)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]-1-pyrrolidinyl}-2-oxoethyl)- ;4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide |