CPDA

Modify Date: 2024-01-09 20:44:44

CPDA Structure
CPDA structure
Common Name CPDA
CAS Number 1415834-63-7 Molecular Weight 388.79500
Density N/A Boiling Point N/A
Molecular Formula C20H15ClF2N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CPDA


CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor that can effectively ameliorate insulin resistance in 3T3-L1 adipocytes.Target: SHIP2in vitro: CPDA was found to enhance insulin signaling.in vivo: CPDA greatly improves abnormal glucose metabolism in diabetic animals. CPDA was also found to improve the abnormal glucose metabolism in db/db mice.

 Names

Name cpda
Synonym More Synonyms

 CPDA Biological Activity

Description CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor that can effectively ameliorate insulin resistance in 3T3-L1 adipocytes.Target: SHIP2in vitro: CPDA was found to enhance insulin signaling.in vivo: CPDA greatly improves abnormal glucose metabolism in diabetic animals. CPDA was also found to improve the abnormal glucose metabolism in db/db mice.
Related Catalog
References

[1]. Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2). Eur J Med Chem. 2013 Apr;62:649-660.

 Chemical & Physical Properties

Molecular Formula C20H15ClF2N2O2
Molecular Weight 388.79500
Exact Mass 388.07900
PSA 51.22000
LogP 4.84640
Storage condition 2-8℃

 Synonyms

N-[4-[(4-Chlorophenyl)methoxy]-2-pyridinyl]-2,6-difluoro-benzeneacetamide
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