Isobutyl-deoxynyboquinone
Modify Date: 2024-01-10 13:41:55
Isobutyl-deoxynyboquinone structure
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Common Name | Isobutyl-deoxynyboquinone | ||
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| CAS Number | 1430798-22-3 | Molecular Weight | 326.352 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Isobutyl-deoxynyboquinoneIsobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner; has improved solubility and biocompatibility in comparison with DNQ; a superior drug candidate for evaluating anticancer activities and tolerability in vivo. |
| Name | Isobutyl-deoxynyboquinone |
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| Description | Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner; has improved solubility and biocompatibility in comparison with DNQ; a superior drug candidate for evaluating anticancer activities and tolerability in vivo. |
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| References | References 1. Parkinson EI, et al. Acc Chem Res. 2015 Oct 20;48(10):2715-23. 2. Lundberg AP, et al. Invest New Drugs. 2017 Apr;35(2):134-144. 3. Parkinson EI, et al. ACS Chem Biol. 2013 Oct 18;8(10):2173-83. View Related Products by Target Other Targets |
| Molecular Formula | C18H18N2O4 |
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| Molecular Weight | 326.352 |