(Acetylmethylene)triphenylphosphorane

Modify Date: 2024-01-02 17:30:40

(Acetylmethylene)triphenylphosphorane structure	Common Name	(Acetylmethylene)triphenylphosphorane
	CAS Number	1439-36-7	Molecular Weight	318.349
	Density	1.1±0.1 g/cm3	Boiling Point	478.5±28.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₁₉OP	Melting Point	203-205 °C(lit.)
	MSDS	Chinese USA	Flash Point	243.2±24.0 °C

Name	(acetylmethylene)triphenylphosphorane
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	478.5±28.0 °C at 760 mmHg
Melting Point	203-205 °C(lit.)
Molecular Formula	C₂₁H₁₉OP
Molecular Weight	318.349
Flash Point	243.2±24.0 °C
Exact Mass	318.117340
PSA	26.88000
LogP	3.22
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.611
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

(Acetylmethylene)triphenylphosphorane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC3900000

CHEMICAL NAME :: 2-Propanone, triphenylphosphoranylidene-

CAS REGISTRY NUMBER :: 1439-36-7

BEILSTEIN REFERENCE NO. :: 0750077

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H19-O-P

MOLECULAR WEIGHT :: 318.37

WISWESSER LINE NOTATION :: 1V1UPR&R&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01327 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/kg/30D-I

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Blood - normocytic anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 9,2641,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1560 mg/kg/26W-I

TOXIC EFFECTS :: Blood - changes in cell count (unspecified) Blood - changes in spleen Biochemical - Metabolism (Intermediary) - other proteins

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 9,2641,1975

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UC3900000

Cyclobutanones through SNi' ring closure, a mechanistic study.

J. Org. Chem. 72 , 2427, (2007)

Mechanistic studies on the intramolecular nucleophilic substitution with allylic rearrangement (SNi' reaction) and a new stereoselective access to substituted cyclobutanones are reported. 4,4-Dialkyl-...

Synthesis , 1359, (2007)

2-Propanone, 1-(triphenylphosphoranylidene)-

EINECS 215-878-2

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(Acetylmethylene)triphenylphosphorane

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MFCD00008774