Divin

Modify Date: 2024-01-15 05:41:05

Divin Structure
Divin structure
Common Name Divin
CAS Number 1443321-11-6 Molecular Weight 372.420
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C22H20N4O2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Divin


A potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells; also is a small molecule inhibitor of bacterial divisome assembly; downregulates the transcription of genes encoding proteins involved in cell division, reduce protein biosynthesis, and affects the spatiotemporal localization of the division machinery.

 Names

Name N'-[(E)-(2-Hydroxy-1-naphthyl)methylene]-3-(2-methyl-1H-benzimidazol-1-yl)propanehydrazide
Synonym More Synonyms

 Divin Biological Activity

Description A potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells; also is a small molecule inhibitor of bacterial divisome assembly; downregulates the transcription of genes encoding proteins involved in cell division, reduce protein biosynthesis, and affects the spatiotemporal localization of the division machinery.
References References 1. Santos TMA, et al. ACS Chem Biol. 2017 Dec 11. doi: 10.1021/acschembio.7b00560. 2. Eun YJ, et al. J Am Chem Soc. 2013 Jul 3;135(26):9768-76. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C22H20N4O2
Molecular Weight 372.420
Exact Mass 372.158630
LogP 5.37
Index of Refraction 1.667

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

N'-[(E)-(2-Hydroxy-1-naphthyl)methylene]-3-(2-methyl-1H-benzimidazol-1-yl)propanehydrazide
MFCD03664181
1H-Benzimidazole-1-propanoic acid, 2-methyl-, 2-[(1E)-(2-hydroxy-1-naphthalenyl)methylene]hydrazide
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