6-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Modify Date: 2024-01-22 20:56:56

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one structure	Common Name	6-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one
	CAS Number	144485-82-5	Molecular Weight	261.66400
	Density	1.51g/cm3	Boiling Point	490ºC at 760mmHg
	Molecular Formula	C₁₂H₈ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	250.1ºC

Name	6-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Density	1.51g/cm3
Boiling Point	490ºC at 760mmHg
Molecular Formula	C₁₂H₈ClN₃O₂
Molecular Weight	261.66400
Flash Point	250.1ºC
Exact Mass	261.03100
PSA	60.92000
LogP	2.33550
Vapour Pressure	9.53E-10mmHg at 25°C
Index of Refraction	1.702

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA2806000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 6-chloro-3-(3-methyl-5-isoxazolyl)-

CAS REGISTRY NUMBER :: 144485-82-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H8-Cl-N3-O2

MOLECULAR WEIGHT :: 261.68

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

5-Chloro-2-nitrobenzoyl chloride structure

5-Chloro-2-nitr...

CAS#:41994-44-9

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6-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure

6-chloro-3-(3-m...

CAS#:144485-82-5

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

Precursor 1
CAS#:41994-44-9 5-Chloro-2-nitr...
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