BI 186908

Modify Date: 2024-04-02 20:21:41

BI 186908 Structure
BI 186908 structure
Common Name BI 186908
CAS Number 1453500-36-1 Molecular Weight 422.485
Density N/A Boiling Point N/A
Molecular Formula C23H26N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI 186908


A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties.

 Names

Name BI 186908

 BI 186908 Biological Activity

Description A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties.
References References 1. Oost T, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3275-80. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR)

 Chemical & Physical Properties

Molecular Formula C23H26N4O4
Molecular Weight 422.485
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