selegiline

Modify Date: 2024-01-10 17:23:33

selegiline Structure
selegiline structure
Common Name selegiline
CAS Number 14611-51-9 Molecular Weight 187.28100
Density 0.954g/cm3 Boiling Point 272.5ºC at 760 mmHg
Molecular Formula C13H17N Melting Point N/A
MSDS N/A Flash Point 108.4ºC
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

 Use of selegiline


Selegiline is a selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

 Names

Name (-)-selegiline
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.954g/cm3
Boiling Point 272.5ºC at 760 mmHg
Molecular Formula C13H17N
Molecular Weight 187.28100
Flash Point 108.4ºC
Exact Mass 187.13600
PSA 3.24000
LogP 2.18260
Vapour Pressure 0.00606mmHg at 25°C
Index of Refraction 1.528

 Safety Information

Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger
Hazard Statements H225-H301 + H311 + H331-H370
Precautionary Statements P210-P260-P280-P301 + P310-P311
Hazard Codes F,T
Risk Phrases 11-23/24/25-39/23/24/25
Safety Phrases 7-16-36/37-45
RIDADR UN 1851
Packaging Group III
Hazard Class 6.1(b)
HS Code 2921499090

 Customs

HS Code 2921499090
Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles48

More Articles
Design and application of an in vivo reporter assay for phenylalanine ammonia-lyase.

Appl. Microbiol. Biotechnol. 97(17) , 7877-85, (2013)

Phenylalanine ammonia-lyase (PAL) is an important enzyme that links primary metabolism to secondary metabolism. Its efficiency is often a critical factor that affects the overall flux of a related met...

A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes.

Infect. Immun. 82(8) , 3492-502, (2014)

(p)ppGpp responds to nutrient limitation through a global change in gene regulation patterns to increase survival. The stringent response has been implicated in the virulence of several pathogenic bac...

Mutational analysis of the (p)ppGpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis.

Arch. Microbiol. 196(8) , 575-88, (2014)

Rel(Mtb), a GTP pyrophosphokinase encoded by the Mycobacterium tuberculosis (Mtb) genome, catalyzes synthesis of (p)ppGpp from ATP and GDP(GTP) and its hydrolysis to GDP(GTP) and pyrophosphate to medi...

 Synonyms

Eldepryl
Jumex
(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine
N-methyl-N-((R)-1-phenylpropan-2-yl)prop-2-yn-1-amine
Selegilina
Emsam
L-Deprenalin
Carbex
methyl(1-phenylpropan-2-yl)(prop-2-yn-1-yl)amine
Selegilinum
(S)-(+)-selegiline
Selegyline
Zelapar
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