10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-

Modify Date: 2024-02-09 10:31:45

10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]- Structure
10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]- structure
Common Name 10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-
CAS Number 14759-04-7 Molecular Weight 354.50900
Density 1.137g/cm3 Boiling Point 503.5ºC at 760mmHg
Molecular Formula C21H26N2OS Melting Point N/A
MSDS N/A Flash Point 258.3ºC

 Names

Name 2-methoxy-10-[2-(1-methylpiperidin-2-yl)ethyl]phenothiazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.137g/cm3
Boiling Point 503.5ºC at 760mmHg
Molecular Formula C21H26N2OS
Molecular Weight 354.50900
Flash Point 258.3ºC
Exact Mass 354.17700
PSA 41.01000
LogP 5.17520
Vapour Pressure 2.89E-10mmHg at 25°C
Index of Refraction 1.597

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SP0875000
CHEMICAL NAME :
Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-
CAS REGISTRY NUMBER :
14759-04-7
BEILSTEIN REFERENCE NO. :
6118065
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H26-N2-O-S
MOLECULAR WEIGHT :
354.55
WISWESSER LINE NOTATION :
T C666 BN ISJ EO1 B2- BT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,27,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIGZAY Niigata Igakkai Zasshi. Niigata Medical Journal. (Niigata Igakkai, 1, Asahi-machi, Niigata 951, Japan) V.60- 1946- Volume(issue)/page/year: 82,607,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
516 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
42 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969

 Safety Information

HS Code 2934300000

 Customs

HS Code 2934300000
Summary 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

KS 33
Oxyridazine
Oxiridazinum