α‑Amylase-IN-1

Modify Date: 2024-01-03 11:59:56

α‑Amylase-IN-1 Structure
α‑Amylase-IN-1 structure
Common Name α‑Amylase-IN-1
CAS Number 148404-10-8 Molecular Weight 310.35
Density N/A Boiling Point N/A
Molecular Formula C18H18N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of α‑Amylase-IN-1


α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]

 Names

Name 1-[3-(4-Hydroxy-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

 α‑Amylase-IN-1 Biological Activity

Description α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]
Related Catalog
Target

IC50: 0.5509 μM (α-Amylase), 53.49 μM (DPPH)

References

[1]. Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8(23):20412-20422.  

 Chemical & Physical Properties

Molecular Formula C18H18N2O3
Molecular Weight 310.35
Exact Mass 310.13200
PSA 62.13000
LogP 2.47190