n-boc-(s)-2-amino-1-butanol

Modify Date: 2024-01-12 16:04:56

n-boc-(s)-2-amino-1-butanol Structure
n-boc-(s)-2-amino-1-butanol structure
Common Name n-boc-(s)-2-amino-1-butanol
CAS Number 150736-72-4 Molecular Weight 189.252
Density 1.0±0.1 g/cm3 Boiling Point 292.9±23.0 °C at 760 mmHg
Molecular Formula C9H19NO3 Melting Point 40-45ºC
MSDS Chinese USA Flash Point 131.0±22.6 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name tert-butyl N-[(2S)-1-hydroxybutan-2-yl]carbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 292.9±23.0 °C at 760 mmHg
Melting Point 40-45ºC
Molecular Formula C9H19NO3
Molecular Weight 189.252
Flash Point 131.0±22.6 °C
Exact Mass 189.136490
PSA 58.56000
LogP 1.37
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.452

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H314
Precautionary Statements P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;
Risk Phrases R22
Safety Phrases S26
RIDADR UN 2923 8/PG 3
HS Code 2924199090

 Synthetic Route

~99%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Hoffmann-La Roche Inc.; Banner, David; Haap, Wolfgang; Kuhn, Bernd; Luebbers, Thomas; Peters, Jens-Uwe; Schulz-Gasch, Tanja Patent: US2013/137687 A1, 2013 ; Location in patent: Paragraph 0177 ;

~%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: AXYS PHARMACEUTICALS, INC. Patent: WO2004/838 A1, 2003 ; Location in patent: Page 73 ; WO 2004/000838 A1

~%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Burk, Mark J.; Johnson, Nicholas B.; Lee, Jeffrey R. Tetrahedron Letters, 1999 , vol. 40, # 36 p. 6685 - 6688

~94%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Banfi, Luca; Guanti, Giuseppe; Riva, Renata; Basso, Andrea; Calcagno, Emiliano Tetrahedron Letters, 2002 , vol. 43, # 22 p. 4067 - 4069

~%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Tetrahedron Letters, , vol. 40, # 36 p. 6685 - 6688

~%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Burk, Mark J.; Johnson, Nicholas B.; Lee, Jeffrey R. Tetrahedron Letters, 1999 , vol. 40, # 36 p. 6685 - 6688

~%

n-boc-(s)-2-amino-1-butanol Structure

n-boc-(s)-2-ami...

CAS#:150736-72-4

Literature: Catalano, John G; Deaton, David N; Furfine, Eric S; Hassell, Annie M; McFadyen, Robert B; Miller, Aaron B; Miller, Larry R; Shewchuk, Lisa M; Willard Jr., Derril H; Wright, Lois L Bioorganic and medicinal chemistry letters, 2004 , vol. 14, # 1 p. 275 - 278

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Carbamic acid, N-[(1S)-1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl [(2S)-1-hydroxy-2-butanyl]carbamate
(S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate
N-Boc-(S)-(−)-2-amino-1-butanol