THREO-DIHYDROBUPROPION

Modify Date: 2024-01-10 17:45:11

THREO-DIHYDROBUPROPION Structure
THREO-DIHYDROBUPROPION structure
Common Name THREO-DIHYDROBUPROPION
CAS Number 153365-82-3 Molecular Weight 241.75700
Density N/A Boiling Point N/A
Molecular Formula C13H20ClNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of THREO-DIHYDROBUPROPION


Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1].

 Names

Name threo-dihydrobupropion
Synonym More Synonyms

 THREO-DIHYDROBUPROPION Biological Activity

Description Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1].
Related Catalog
References

[1]. Andrea R Masters, et al. Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:201-208.

 Chemical & Physical Properties

Molecular Formula C13H20ClNO
Molecular Weight 241.75700
Exact Mass 241.12300
PSA 32.26000
LogP 3.54090

 Synonyms

(R*,R*)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL MALEATE
(R*,R*)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL
threo-Hydroxy Bupropion HCl
THREO-HYDROBUPROPION
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