Antazoline
Antazoline structure
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Common Name | Antazoline | ||
|---|---|---|---|---|
| CAS Number | 154-68-7 | Molecular Weight | 363.348 | |
| Density | 0.975 g/mL at 25 °C(lit.) | Boiling Point | 235-236 °C(lit.) | |
| Molecular Formula | C17H22N3O4P | Melting Point | 120-122ºC | |
| MSDS | Chinese USA | Flash Point | >230 °F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of AntazolineAntazoline phosphate is an antihistamine with anticholinergic properties used to relieve nasal congestion and the symptoms of allergic conjunctivitis. Antazoline is an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles. |
| Name | N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline,phosphoric acid |
|---|---|
| Synonym | More Synonyms |
| Density | 0.975 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 235-236 °C(lit.) |
| Melting Point | 120-122ºC |
| Molecular Formula | C17H22N3O4P |
| Molecular Weight | 363.348 |
| Flash Point | >230 °F |
| Exact Mass | 363.134796 |
| PSA | 115.20000 |
| LogP | 1.53070 |
| Vapour Pressure | 3.31E-09mmHg at 25°C |
| Index of Refraction | n20/D 1.517(lit.) |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332-H315-H319-H335 |
| Precautionary Statements | P261-P280-P301 + P312 + P330-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.
Eur. J. Ophthalmol. 20(5) , 811-8, (2010) To compare the effects of topical antiallergic eyedrops in relieving the signs and symptoms of patients with allergic conjunctival pathology.In this multicenter, single-masked, randomized study, 240 p... |
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Simultaneous determination of antazoline and naphazoline by the net analyte signal standard addition method and spectrophotometric technique.
J. AOAC Int. 93(6) , 1995-2001, (2010) A novel net analyte signal standard addition method (NASSAM) was used for simultaneous determination of the drugs anthazoline and naphazoline. The NASSAM can be applied for determination of analytes i... |
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Determination of antihistamines based on the formation of mixed aggregates with surfactants.
Analyst 123(5) , 1079-84, (1998) The determination of antihistamines based on the measurement of the critical micelle concentration (c.m.c.) of mixed sodium dodecyl sulfate (SDS)-antihistamine aggregates is proposed. The dye Coomassi... |
| 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, phosphate (1:1) |
| Antazoline Phosphate |
| Antazoline phosphate (USP) |
| UNII-VPR5FPH326 |
| EINECS 205-831-4 |
| MFCD00054317 |
| Antazoline phosphate salt |
| 2-(N-Benzylanilinomethyl)-2-imidazoline |
| N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline phosphate (1:1) |
| 2-(N-PHENYL-N-BENZYL-AMINOMETHYL)-IMIDAZOLINE |