SBFI-26
Modify Date: 2024-01-04 10:26:05
SBFI-26 structure
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Common Name | SBFI-26 | ||
|---|---|---|---|---|
| CAS Number | 1541209-75-9 | Molecular Weight | 422.472 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 641.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C28H22O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 219.5±25.0 °C | |
Use of SBFI-26SBFI-26 (SBFI26) is a small molecule inhibitor of epidermal- and brain-specific FABP5 and FABP7 that effectively increases anandamide signaling; dose-dependently reduces mechanical hyperalgesia in vivo, demonstrates significant analgesic and anti-inflammatory properties; also suppresses the malignant progression of castration resistant prostate cancer cells by competitively binding to oncogenic FABP5. |
| Name | (1R,2R,3R,4R)-3-[(1-Naphthyloxy)carbonyl]-2,4-diphenylcyclobutanecarboxylic acid |
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| Synonym | More Synonyms |
| Description | SBFI-26 (SBFI26) is a small molecule inhibitor of epidermal- and brain-specific FABP5 and FABP7 that effectively increases anandamide signaling; dose-dependently reduces mechanical hyperalgesia in vivo, demonstrates significant analgesic and anti-inflammatory properties; also suppresses the malignant progression of castration resistant prostate cancer cells by competitively binding to oncogenic FABP5. |
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| References | References 1. Peng X, et al. Mol Pain. 2017 Jan;13:1744806917697007. 2. Hsu HC, et al. Biochemistry. 2017 Jul 11;56(27):3454-3462. 3. Al-Jameel W, et al. Oncotarget. 2017 May 9;8(19):31041-31056. 4. Thanos PK, et al. Front Psychiatry. 2016 Apr 5;7:54. View Related Products by Target FABP |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 641.1±55.0 °C at 760 mmHg |
| Molecular Formula | C28H22O4 |
| Molecular Weight | 422.472 |
| Flash Point | 219.5±25.0 °C |
| Exact Mass | 422.151794 |
| LogP | 6.35 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.665 |
| 1,3-Cyclobutanedicarboxylic acid, 2,4-diphenyl-, mono(1-naphthalenyl) ester, (1α,2α,3β,4β)- |
| (1R,2R,3R,4R)-3-[(1-Naphthyloxy)carbonyl]-2,4-diphenylcyclobutanecarboxylic acid |