4-[6-(2-Fluoroethoxy)-2-quinolinyl]aniline structure
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Common Name | 4-[6-(2-Fluoroethoxy)-2-quinolinyl]aniline | ||
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CAS Number | 1573029-17-0 | Molecular Weight | 282.312 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 470.3±45.0 °C at 760 mmHg | |
Molecular Formula | C17H15FN2O | Melting Point | N/A | |
MSDS | N/A | Flash Point | 238.2±28.7 °C |
Use of 4-[6-(2-Fluoroethoxy)-2-quinolinyl]anilineTHK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. 18F-THK523 is a potent tau imaging radiotracer. 18F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease[1]. |
Name | 4-[6-(2-Fluoroethoxy)-2-quinolinyl]aniline |
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Synonym | More Synonyms |
Description | THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. 18F-THK523 is a potent tau imaging radiotracer. 18F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease[1]. |
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Related Catalog | |
In Vivo | THK-523 crosses the blood–brain barrier in mice and the in vivo retention rate in the brain of Tau transgenic mice increased[1]. Animal Model: Brain of tau transgenic mice[1] Dosage: 0.35 μg/kg Administration: Intravenous injection;25-30 mins Result: Overexpressed Tau in brain. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 470.3±45.0 °C at 760 mmHg |
Molecular Formula | C17H15FN2O |
Molecular Weight | 282.312 |
Flash Point | 238.2±28.7 °C |
Exact Mass | 282.116852 |
LogP | 3.01 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.635 |
4-[6-(2-Fluoroethoxy)-2-quinolinyl]aniline |
Benzenamine, 4-[6-(2-fluoroethoxy)-2-quinolinyl]- |
THK-523 |