4-(Trifluoromethyl)nicotinic acid structure
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Common Name | 4-(Trifluoromethyl)nicotinic acid | ||
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CAS Number | 158063-66-2 | Molecular Weight | 191.107 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 290.4±40.0 °C at 760 mmHg | |
Molecular Formula | C7H4F3NO2 | Melting Point | 146-148 °C(lit.) | |
MSDS | USA | Flash Point | 129.4±27.3 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Name | 4-(Trifluoromethyl)nicotinic acid |
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Synonym | More Synonyms |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 290.4±40.0 °C at 760 mmHg |
Melting Point | 146-148 °C(lit.) |
Molecular Formula | C7H4F3NO2 |
Molecular Weight | 191.107 |
Flash Point | 129.4±27.3 °C |
Exact Mass | 191.019409 |
PSA | 50.19000 |
LogP | 1.12 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.475 |
Synonym:4-(Trifluoromethyl)pyridine-3-carboxylic aci Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 158063-66-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 145 - 148 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H4F3NO2 Molecular Weight: 191 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases, amines. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 158063-66-2 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-(Trifluoromethyl)nicotinic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 158063-66-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 158063-66-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 158063-66-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi:Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36-S37/39 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933399090 |
~82% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Sankyo Agro Company, Limited Patent: EP1460071 A1, 2004 ; Location in patent: Page 40; 41 ; |
~89% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Sankyo Agro Company, Limited Patent: EP1460071 A1, 2004 ; Location in patent: Page 40 ; |
~47% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Sankyo Agro Company, Limited Patent: EP1460071 A1, 2004 ; Location in patent: Page 41 ; |
~89% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Cottet, Fabrice; Marull, Marc; Lefebvre, Olivier; Schlosser, Manfred European Journal of Organic Chemistry, 2003 , # 8 p. 1559 - 1568 |
~83% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Schlosser, Manfred; Marull, Marc European Journal of Organic Chemistry, 2003 , # 8 p. 1569 - 1575 |
~81% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: Schlosser, Manfred; Marull, Marc European Journal of Organic Chemistry, 2003 , # 8 p. 1569 - 1575 |
~% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: European Journal of Organic Chemistry, , # 8 p. 1559 - 1568 |
~% 4-(Trifluoromet... CAS#:158063-66-2 |
Literature: European Journal of Organic Chemistry, , # 8 p. 1569 - 1575 |
Precursor 9 | |
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DownStream 5 | |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
T6NJ CVQ DXFFF |
3-Pyridinecarboxylic acid, 4-(trifluoromethyl)- |
4-(Trifluoromethyl)-3-pyridinecarboxylic acid |
MFCD00082626 |
4-(Trifluoromethyl)nicotinic acid |
4-(Trifluoromethyl)pyridine-3-carboxylic acid |