BMS-871

Modify Date: 2024-08-13 12:49:18

BMS-871 Structure
BMS-871 structure
Common Name BMS-871
CAS Number 1584631-89-9 Molecular Weight 536.555
Density N/A Boiling Point N/A
Molecular Formula C29H27F3N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-871


BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively; inhibits TALL-1 tumor cell proliferation with IC50 of 4 nM, displays robust in vivo efficacy in Notch-dependent leukemia and triple negative breast cancer xenografts.

 Names

Name BMS-871

 BMS-871 Biological Activity

Description BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively; inhibits TALL-1 tumor cell proliferation with IC50 of 4 nM, displays robust in vivo efficacy in Notch-dependent leukemia and triple negative breast cancer xenografts.
References References 1. Shan W, et al. Bioorg Med Chem Lett. 2015 May 1;25(9):1905-9. View Related Products by Target Notch

 Chemical & Physical Properties

Molecular Formula C29H27F3N4O3
Molecular Weight 536.555
Top Suppliers:I want be here



Get all suppliers and price by the below link:

BMS-871 suppliers

BMS-871 price