KDM5-C49
Modify Date: 2024-04-03 11:42:55
KDM5-C49 structure
|
Common Name | KDM5-C49 | ||
|---|---|---|---|---|
| CAS Number | 1596348-16-1 | Molecular Weight | 308.376 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 531.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H24N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 275.0±30.1 °C | |
Use of KDM5-C49KDM5-C49 is a potent, selective KDM5 inhibitor with IC50 of 25, 30 and 59 nM for KDM5A, B and C, respectively; displays 25-100-fold selectivity over KDM6B, 2-30-fold selectivity over KDM4 family, but with less cell-permeablity. |
| Name | KDM5-C49 |
|---|---|
| Synonym | More Synonyms |
| Description | KDM5-C49 is a potent, selective KDM5 inhibitor with IC50 of 25, 30 and 59 nM for KDM5A, B and C, respectively; displays 25-100-fold selectivity over KDM6B, 2-30-fold selectivity over KDM4 family, but with less cell-permeablity. |
|---|---|
| References | References 1. Johansson C, et. Nat Chem Biol. 2016 Jul;12(7):539-45. 2. Horton JR, et al. Cell Chem Biol. 2016 Jul 21;23(7):769-81. View Related Products by Target Histone Demethylase |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.0±50.0 °C at 760 mmHg |
| Molecular Formula | C15H24N4O3 |
| Molecular Weight | 308.376 |
| Flash Point | 275.0±30.1 °C |
| Exact Mass | 308.184845 |
| LogP | -0.13 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.552 |
| 4-Pyridinecarboxylic acid, 2-[[[2-[[2-(dimethylamino)ethyl]ethylamino]-2-oxoethyl]amino]methyl]- |
| 6OQJ5L847C |
| KDM5-C49 |
| MFCD31539980 |
| 2-{[(2-{[2-(Dimethylamino)ethyl](ethyl)amino}-2-oxoethyl)amino]methyl}isonicotinic acid |