ACY-957 structure
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Common Name | ACY-957 | ||
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CAS Number | 1609389-52-7 | Molecular Weight | 429.537 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 602.7±55.0 °C at 760 mmHg | |
Molecular Formula | C24H23N5OS | Melting Point | N/A | |
MSDS | N/A | Flash Point | 318.3±31.5 °C |
Use of ACY-957ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. |
Name | ACY-957 |
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Synonym | More Synonyms |
Description | ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. |
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Related Catalog | |
Target |
HDAC1:7 nM (IC50) HDAC2:18 nM (IC50) HDAC3:1300 nM (IC50) |
In Vitro | ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC50 of 304 nM for HDAC2 in primary hematopoietic progenitors[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 602.7±55.0 °C at 760 mmHg |
Molecular Formula | C24H23N5OS |
Molecular Weight | 429.537 |
Flash Point | 318.3±31.5 °C |
Exact Mass | 429.162323 |
LogP | 2.73 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.726 |
Storage condition | 2-8℃ |
6-Quinolinecarboxamide, N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)- |
N-[2-Amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-6-quinolinecarboxamide |