Linsidomine hydrochloride structure
|
Common Name | Linsidomine hydrochloride | ||
---|---|---|---|---|
CAS Number | 16142-27-1 | Molecular Weight | 206.630 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C6H11ClN4O2 | Melting Point | 186 °C | |
MSDS | Chinese USA | Flash Point | N/A |
Use of Linsidomine hydrochlorideSIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation[1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion[2]. |
Name | 3-Morpholinosydnonimine hydrochloride |
---|---|
Synonym | More Synonyms |
Description | SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation[1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion[2]. |
---|---|
Related Catalog | |
References |
Melting Point | 186 °C |
---|---|
Molecular Formula | C6H11ClN4O2 |
Molecular Weight | 206.630 |
Exact Mass | 206.057053 |
PSA | 67.28000 |
Storage condition | -20°C |
Water Solubility | soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
HS Code | 2934999090 |
Precursor 0 | |
---|---|
DownStream 2 | |
HS Code | 2934999090 |
---|---|
Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.
Cell Death Dis. 5 , e1410, (2014) Platelet activation is a frontline response to injury, not only essential for clot formation but also important for tissue repair. Indeed, the reparative influence of platelets has long been exploited... |
|
Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells.
Exp. Neurol. 233(1) , 154-62, (2012) The role of taurine in regulating glucose-induced nitrosative stress has been examined in human Schwann cells, a model for understanding the pathogenesis of diabetic neuropathy. Exposure to high gluco... |
|
Comparative kinetics of thiol oxidation in two distinct free-radical generating systems: SIN-1 versus AAPH.
Free Radic. Res. 46(10) , 1190-200, (2012) To study oxidative stress in biological systems, chemical compounds capable of producing free radicals have been widely used. Here, we compared two free-radical generators, 3-morpholinosydnonimine (SI... |
3-(4-morpholinyl)-5-sydnone imine hydrochloride |
[3-(4-Morpholinyl)-1,2,3-oxadiazol-3-ium-5-yl]azanide hydrochloride (1:1) |
3-(4-Morpholinyl)sydnone imine hydrochloride Linsidomine hydrochloride SIN-1 hydrochloride |
T6N DOTJ A- AT5KNOYJ DUM &&sydnone |
SIN-I HYDROCHLORIDE |
LINSIDOMINE HCL |
3-(4-morpholinyl)-sydnonimine hydrochloride |
[3-(Morpholin-4-yl)-1,2,3-oxadiazol-3-ium-5-yl]azanide hydrochloride (1:1) |
MFCD00221615 |
3-(4-Morpholinyl)sydnone imine hydrochloride |
LinsidoMine Chlorhydrate |
3-morpholinosydnone imine hydrochloride |
1,2,3-Oxadiazolium, 5-amino-3-(4-morpholinyl)-, inner salt, hydrochloride (1:1) |
MolsidoMine IMpurity A |
SIN-1 |
SIN-1 CHLORIDE |
B-HT 933 dihydrochloride |
3-morpholino-sydnonimine hydrochloride |
SIN-1 HCL |
3-Morpholinosydnonimine hydrochloride |
5-Imino-3-(morpholin-4-yl)-5H-1,2,3-oxadiazol-3-ium-2-ide hydrochloride (1:1) |
SIN-1 HYDROCHLORIDE |
EINECS 247-207-4 |
LINSIDOMINE |