ML398
Modify Date: 2024-10-07 13:43:41
ML398 structure
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Common Name | ML398 | ||
|---|---|---|---|---|
| CAS Number | 1620203-88-4 | Molecular Weight | 315.837 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 421.3±30.0 °C at 760 mmHg | |
| Molecular Formula | C19H22ClNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 208.6±24.6 °C | |
Use of ML398ML398 (CID72737723) is a potent, selective, highly brain penetrant dopamine 4 (D4) receptor antagonist with IC50/Ki of 130 nM/60 nM; shows excellent selectivity (>100-fold) against the other dopamine receptor subtypes (D1,2S,2L,3,5; >20 uM); reverses cocaine-induced hyperlocomotion at 10 mg/kg in vivo. |
| Name | ML398 |
|---|---|
| Synonym | More Synonyms |
| Description | ML398 (CID72737723) is a potent, selective, highly brain penetrant dopamine 4 (D4) receptor antagonist with IC50/Ki of 130 nM/60 nM; shows excellent selectivity (>100-fold) against the other dopamine receptor subtypes (D1,2S,2L,3,5; >20 uM); reverses cocaine-induced hyperlocomotion at 10 mg/kg in vivo. |
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| References | References 1. Berry CB, et al. ACS Med Chem Lett. 2014 Jul 9;5(9):1060-4. View Related Products by Target Dopamine Receptor |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 421.3±30.0 °C at 760 mmHg |
| Molecular Formula | C19H22ClNO |
| Molecular Weight | 315.837 |
| Flash Point | 208.6±24.6 °C |
| Exact Mass | 315.138977 |
| LogP | 4.34 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.574 |
| ML398 |
| (2R)-4-(4-Chlorobenzyl)-2-(2-phenylethyl)morpholine |
| Morpholine, 4-[(4-chlorophenyl)methyl]-2-(2-phenylethyl)-, (2R)- |