Polygalaxanthone III

Modify Date: 2024-01-06 10:48:39

Polygalaxanthone III Structure
Polygalaxanthone III structure
 Common Name Polygalaxanthone III
CAS Number 162857-78-5 Molecular Weight 568.481
Density 1.83 Boiling Point 973.2±65.0 °C at 760 mmHg
Molecular Formula C25H28O15 Melting Point 180-183℃
MSDS N/A Flash Point 327.7±27.8 °C

 Use of Polygalaxanthone III


Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].

 Names

Name Polygalaxanthone III
Synonym More Synonyms

 Polygalaxanthone III Biological Activity

Description Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].
Related Catalog
References

[1]. Li ZL, et al. Effect of oligosaccharide esters and polygalaxanthone Ill from Polygala tenuifolia willd towards cytochrome P450. Zhongguo Zhong Yao Za Zhi. 2014 Nov;39(22):4459-63.

 Chemical & Physical Properties

Density 1.83
Boiling Point 973.2±65.0 °C at 760 mmHg
Melting Point 180-183℃
Molecular Formula C25H28O15
Molecular Weight 568.481
Flash Point 327.7±27.8 °C
Exact Mass 568.142822
LogP -0.31
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.765

 Safety Information

Safety Phrases S24/25

 Synonyms

D-Glucitol, 1,5-anhydro-6-O-[(2R,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-1-C-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-, (1S)-
(1S)-1,5-Anhydro-6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-1-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
polygalaxanthone III
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Chemsrc provides Polygalaxanthone III(CAS#:162857-78-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Polygalaxanthone III are included as well.>> amp version: Polygalaxanthone III

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