antcin A

Modify Date: 2024-01-02 15:31:27

antcin A Structure
antcin A structure
Common Name antcin A
CAS Number 163597-24-8 Molecular Weight 454.64
Density N/A Boiling Point N/A
Molecular Formula C29H42O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of antcin A


Antcin A is a potent NLRP3 inhibitor that inhibits the assembly and activation of the NLRP3 inflammasome. Antcin A can inhibit Kupffer cell pyroptosis and has liver protective activity. Antcin A can be used to study inflammation, such as non-alcoholic fatty liver disease[1].

 Names

Name (2S,6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14R,17R)-4,10,13-trimethyl-3,11-dioxo-2,4,5,6,7,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid
Synonym More Synonyms

 antcin A Biological Activity

Description Antcin A is a potent NLRP3 inhibitor that inhibits the assembly and activation of the NLRP3 inflammasome. Antcin A can inhibit Kupffer cell pyroptosis and has liver protective activity. Antcin A can be used to study inflammation, such as non-alcoholic fatty liver disease[1].
Related Catalog
Target

NLRP3[1].

References

[1]. Ruan S, et al. Antcin A alleviates pyroptosis and inflammatory response in Kupffercells of non-alcoholic fatty liver disease by targeting NLRP3. Int Immunopharmacol. 2021 Nov;100:108126.  

 Chemical & Physical Properties

Molecular Formula C29H42O4
Molecular Weight 454.64
Exact Mass 454.30800
PSA 71.44000
LogP 6.39680

 Synonyms

(4alpha,5alpha,25S)-4-Methyl-3,11-dioxoergosta-8,24(28)-dien-26-oic acid
anticin A
Ergosta-8,24(28)-dien-26-oicacid,4-methyl-3,11-dioxo-,(4a,5a,25S)
AntcinA
Top Suppliers:I want be here

Get all suppliers and price by the below link:

antcin A suppliers

antcin A price