Tofacitinib metabolite-1

Modify Date: 2024-01-09 19:08:50

Tofacitinib metabolite-1 structure	Common Name	Tofacitinib metabolite-1
	CAS Number	1640971-51-2	Molecular Weight	328.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₀N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tofacitinib metabolite-1

Tofacitinib metabolite-1 is a metabolite of Tofacitinib (HY-40354), a JAK inhibitor. Tofacitinib metabolite-1 can be used in the pharmacokinetics and metabolism studies of tofacitinib[1][2].

Name	Tofacitinib metabolite-1

Description	Tofacitinib metabolite-1 is a metabolite of Tofacitinib (HY-40354), a JAK inhibitor. Tofacitinib metabolite-1 can be used in the pharmacokinetics and metabolism studies of tofacitinib[1][2].
Related Catalog	Research Areas >> Others
References	[1]. Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73. [2]. Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.

Description

Tofacitinib metabolite-1 is a metabolite of Tofacitinib (HY-40354), a JAK inhibitor. Tofacitinib metabolite-1 can be used in the pharmacokinetics and metabolism studies of tofacitinib[1][2].

Related Catalog

Research Areas >> Others

References

[1]. Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73.

[2]. Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.

Molecular Formula	C₁₆H₂₀N₆O₂
Molecular Weight	328.37

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