Podophyllotoxin β-D-glucoside

Modify Date: 2024-01-02 20:01:33

Podophyllotoxin β-D-glucoside Structure
Podophyllotoxin β-D-glucoside structure
Common Name Podophyllotoxin β-D-glucoside
CAS Number 16481-54-2 Molecular Weight 576.546
Density 1.5±0.1 g/cm3 Boiling Point 781.3±60.0 °C at 760 mmHg
Molecular Formula C28H32O13 Melting Point 152-154℃
MSDS N/A Flash Point 258.2±26.4 °C

 Use of Podophyllotoxin β-D-glucoside


Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects[1].

 Names

Name Podophyllotoxin, 3-.β.-D-glucopyranoside
Synonym More Synonyms

 Podophyllotoxin β-D-glucoside Biological Activity

Description Podophyllotoxin glucoside is a podophyllotoxin derivative, has anti-tumor effects[1].
Related Catalog
References

[1]. K R Hande, et al. Etoposide: four decades of development of a topoisomerase II inhibitor. Eur J Cancer

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 781.3±60.0 °C at 760 mmHg
Melting Point 152-154℃
Molecular Formula C28H32O13
Molecular Weight 576.546
Flash Point 258.2±26.4 °C
Exact Mass 576.184265
PSA 171.83000
LogP -0.66
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.660
Storage condition 2-8C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP9002050
CHEMICAL NAME :
Podophyllotoxin, 4,6-O-benzylidene-beta-D-glucopyranoside
CAS REGISTRY NUMBER :
16481-54-2
LAST UPDATED :
199012
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C28-H32-O13
MOLECULAR WEIGHT :
576.60
WISWESSER LINE NOTATION :
T E5 C665 FVO NO PO OHTT&&J DR CO1 DO1 EO1& JO- HT66 BO DO GOTJ CR& IQ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Cells - not otherwise specified
DOSE/DURATION :
30 mg/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,2998,1977

 Synonyms

Podophyllotoxin-7-O-glucoside
Podophyllotoxin 4-O-glucoside
(5R,5aR,8aR,9R)-8-Oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl β-D-glucopyranoside
Podophyllotoxin glucoside
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-(β-D-glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)-
Podophyllotoxin, 3-β-D-glucopyranoside
Podophyllotoxin-4-O-glucoside
Podophyllotoxin-β-D-glucoside
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Podophyllotoxin β-D-glucoside suppliers

Podophyllotoxin β-D-glucoside price