2-Fluorohexadecanoic acid

Modify Date: 2023-01-31 11:35:17

2-Fluorohexadecanoic acid Structure
2-Fluorohexadecanoic acid structure
Common Name 2-Fluorohexadecanoic acid
CAS Number 16518-94-8 Molecular Weight 274.414
Density 0.9±0.1 g/cm3 Boiling Point 376.1±12.0 °C at 760 mmHg
Molecular Formula C16H31FO2 Melting Point N/A
MSDS N/A Flash Point 181.3±19.6 °C

 Use of 2-Fluorohexadecanoic acid


2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines[1].

 Names

Name 2-fluorohexadecanoic acid
Synonym More Synonyms

 2-Fluorohexadecanoic acid Biological Activity

Description 2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines[1].
Related Catalog
References

[1]. Shabierjiang Jiapaer 1, et al. Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma. Curr Pharm Des. 2020;26(36):4675-4684.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 376.1±12.0 °C at 760 mmHg
Molecular Formula C16H31FO2
Molecular Weight 274.414
Flash Point 181.3±19.6 °C
Exact Mass 274.230804
PSA 37.30000
LogP 7.03
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.444

 Safety Information

HS Code 2915900090

 Synthetic Route

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2-Fluorohexadecanoic acid Structure

2-Fluorohexadec...

CAS#:16518-94-8

Literature: Kirin Beer Kabushiki Kaisha Patent: US5461036 A1, 1995 ;

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2-Fluorohexadecanoic acid Structure

2-Fluorohexadec...

CAS#:16518-94-8

Literature: Gershon; Parmegiani Journal of medicinal chemistry, 1967 , vol. 10, # 2 p. 186 - 188

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2-Fluorohexadecanoic acid Structure

2-Fluorohexadec...

CAS#:16518-94-8

Literature: Gershon; Parmegiani Journal of medicinal chemistry, 1967 , vol. 10, # 2 p. 186 - 188

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Synonyms

2-Fluor-palmitinsaeure
(2RS)-fluorohexadecanoic acid
Hexadecanoic acid,2-fluoro
Hexadecanoic acid, 2-fluoro-
2-Fluorohexadecanoic acid
2-fluoro-hexadecanoic acid