3,5-Pyrazolidinedione,4-butyl-4-hydroxy-1,2-diphenyl-
Modify Date: 2024-01-05 16:32:10
3,5-Pyrazolidinedione,4-butyl-4-hydroxy-1,2-diphenyl- structure
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Common Name | 3,5-Pyrazolidinedione,4-butyl-4-hydroxy-1,2-diphenyl- | ||
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| CAS Number | 16860-43-8 | Molecular Weight | 324.37400 | |
| Density | 1.256g/cm3 | Boiling Point | 462.3ºC at 760mmHg | |
| Molecular Formula | C19H20N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 233.4ºC | |
Use of 3,5-Pyrazolidinedione,4-butyl-4-hydroxy-1,2-diphenyl-4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory drug (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS)[1]. |
| Name | 4-Hydroxy Phenylbutazone |
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| Synonym | More Synonyms |
| Description | 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory drug (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS)[1]. |
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| Related Catalog | |
| In Vitro | 4-hydroxyphenylbutazone is isolated from incubations of phenylbutazone with either ram seminal vesicle microsomes or horseradish peroxidase. 4-hydroxyphenylbutazone is ineffective inhibitor of PHS cyclooxygenase[1]. |
| References |
| Density | 1.256g/cm3 |
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| Boiling Point | 462.3ºC at 760mmHg |
| Molecular Formula | C19H20N2O3 |
| Molecular Weight | 324.37400 |
| Flash Point | 233.4ºC |
| Exact Mass | 324.14700 |
| PSA | 60.85000 |
| LogP | 3.03270 |
| Vapour Pressure | 2.41E-09mmHg at 25°C |
| Index of Refraction | 1.615 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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HPLC method for the determination of 4-hydroxyphenylbutazone in phenylbutazone.
Acta Pharm. Hung. 50(4) , 173-6, (1980)
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| 4-Butyl-4-hydroxy-1,2-diphenyl-3,5-pyrazolidinedione 4-Hydroxyphenylbutazone |
| 4-butyl-4-hydroxy-1,2-diphenylpyrazolidine-3,5-dione |
| Phenylbutazone impurity B |