Azide-PEG4-Tos
Azide-PEG4-Tos structure
|
Common Name | Azide-PEG4-Tos | ||
|---|---|---|---|---|
| CAS Number | 168640-82-2 | Molecular Weight | 373.42500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H23N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Azide-PEG4-TosAzide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-1-(2-methylphenyl)sulfonylethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C15H23N3O6S |
|---|---|
| Molecular Weight | 373.42500 |
| Exact Mass | 373.13100 |
| PSA | 140.19000 |
| LogP | 1.98076 |
| Storage condition | 2-8°C |
|
~93%
Azide-PEG4-Tos CAS#:168640-82-2 |
| Literature: Yue, Xuyi; Feng, Yue; Yu, Y. Bruce Journal of Fluorine Chemistry, 2013 , vol. 152, p. 173 - 181 |
|
~78%
Azide-PEG4-Tos CAS#:168640-82-2 |
| Literature: Dao, Kinh-Luan; Sawant, Rupa R.; Hendricks, J. Adam; Ronga, Victoria; Torchilin, Vladimir P.; Hanson, Robert N. Bioconjugate Chemistry, 2012 , vol. 23, # 4 p. 785 - 795 |
|
~%
Azide-PEG4-Tos CAS#:168640-82-2 |
| Literature: Meunier, Serge J.; Wu, Quigquan; Wang, Sho-Nong; Roy, Rene Canadian Journal of Chemistry, 1997 , vol. 75, # 11 p. 1472 - 1482 |
|
~%
Azide-PEG4-Tos CAS#:168640-82-2 |
| Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984 |
|
~%
Azide-PEG4-Tos CAS#:168640-82-2 |
| Literature: Yue, Xuyi; Feng, Yue; Yu, Y. Bruce Journal of Fluorine Chemistry, 2013 , vol. 152, p. 173 - 181 |
CAS#:31521-83-2| 11-azido-3,6,9-trioxa-undecanyl p-toluenesulfonate |
| 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate |
| toluene-4-sulfonic acid 2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl ester |
| 2-[2-[2-(2-AZIDOETHOXY)ETHOXY]ETHOXY]-1-(P-TOLUENESULFONYL)-ETHANOL |
| 2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethyl tosylate |