Platinum,diamminetetrachloro-, (OC-6-11)-

Modify Date: 2024-01-06 20:18:21

Platinum,diamminetetrachloro-, (OC-6-11)- Structure
Platinum,diamminetetrachloro-, (OC-6-11)- structure
Common Name Platinum,diamminetetrachloro-, (OC-6-11)-
CAS Number 16893-06-4 Molecular Weight 366.91900
Density N/A Boiling Point N/A
Molecular Formula Cl4H2N2Pt++++ Melting Point >300ºC(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS06 GHS08
GHS05, GHS06, GHS08
Signal Word Danger

 Names

Name trans-Diamminetetrachloroplatinum(IV), Pt 52.6%
Synonym More Synonyms

 Chemical & Physical Properties

Melting Point >300ºC(lit.)
Molecular Formula Cl4H2N2Pt++++
Molecular Weight 366.91900
Exact Mass 364.86200
PSA 29.26000
LogP 2.54650
Vapour Pressure 5990mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2485802
CHEMICAL NAME :
Platinum(IV), diamminetetrachloro-, (E)-
CAS REGISTRY NUMBER :
16893-06-4
LAST UPDATED :
199410
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
Cl4-H6-N2-Pt
MOLECULAR WEIGHT :
370.97

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
50 umol/L
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 10,27,1975

 Safety Information

Symbol GHS05 GHS06 GHS08
GHS05, GHS06, GHS08
Signal Word Danger
Hazard Statements H301-H317-H318-H334
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases S26;S36
RIDADR UN 3288
Packaging Group III
Hazard Class 6.1(b)

 Articles3

More Articles
Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity.

Cancer Res. 44(5) , 2043-51, (1984)

Several effects of four diamminechloroplatinum compounds (II and IV) in Chinese hamster ovary cells were studied. The two cis-compounds [cis-diamminedichloroplatinum(II) and cis-diamminetetrachloropla...

Toxicity, mutagenicity and induction of recA protein in Escherichia coli treated with cis-diamminedichloroplatinum(II) and cis-diamminetetrachloroplatinum(IV).

Chem. Biol. Interact. 60(2) , 207-15, (1986)

After exposure of bacteria to equal concentrations of cis-diamminedichloroplatinum(II) (DDP) and cis-diamminetetrachloroplatinum(IV) (DTP), the intracellular concentration of DTP was an order of magni...

Detection of DNA strand breaks in Escherichia coli treated with platinum(IV) antitumor compounds.

Chem. Biol. Interact. 74(3) , 343-52, (1990)

DNA strand breaks were observed in bacteria treated with Pt(IV) but not Pt(II) antitumor compounds by two methods. First, compounds which cause DNA strand breaks produced an SOS induction signal which...

 Synonyms

trans-[PtCl4(NH3)2]
Tetrachloro-trans-diammin-platin(IV)
CIS-DIAMMINETETRACHLOROPLATINUM(IV)
trans-bisamminetetrachloroplatinum
trans Tetrachlorodiammine platinum
MFCD00050045
(e)-platinum(iv
trans-[Pt(NH3)2Cl4]
CIS-TETRACHLORODIAMMINE PLATINUM (IV)
{Pt<a2>Cl4}
DIAMMINETETRACHLOROPLATINATE (IV)
trans-diamminetetrachloroplatinum
(oc-6-11)-platinu
trans-Platinumdiammine tetrachloride
trans-diamminetetrachloroplatinum(IV)
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