SYM2206 structure
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Common Name | SYM2206 | ||
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CAS Number | 173952-44-8 | Molecular Weight | 366.41400 | |
Density | 1.37g/cm3 | Boiling Point | N/A | |
Molecular Formula | C20H22N4O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of SYM2206SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM).IC50 value: 2.8 μMTarget: AMPA receptorSYM 2206 exerts anticonvulsant effects, elevates the threshold for maximal electroshock-induced seizures in mice. TID20 and TID50(threshold increasing doses by 20% and 50%) values for SYM 2206 are 4.25 and 10.56 mg/kg in the MEST test in mice, respectively. |
Name | SYM 2206,(±)-4-(4-Aminophenyl)-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine |
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Synonym | More Synonyms |
Description | SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM).IC50 value: 2.8 μMTarget: AMPA receptorSYM 2206 exerts anticonvulsant effects, elevates the threshold for maximal electroshock-induced seizures in mice. TID20 and TID50(threshold increasing doses by 20% and 50%) values for SYM 2206 are 4.25 and 10.56 mg/kg in the MEST test in mice, respectively. |
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Related Catalog | |
References |
Density | 1.37g/cm3 |
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Molecular Formula | C20H22N4O3 |
Molecular Weight | 366.41400 |
Exact Mass | 366.16900 |
PSA | 89.18000 |
LogP | 3.59170 |
Index of Refraction | 1.673 |
Storage condition | 2-8℃ |
TRIS hydrochloride |
SYM 2206 |
SYM2206 |