Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate

Modify Date: 2024-04-05 10:18:37

Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate Structure
Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate structure
Common Name Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate
CAS Number 175277-73-3 Molecular Weight 278.61500
Density 1.47g/cm3 Boiling Point 325ºC at 760mmHg
Molecular Formula C10H6ClF3N2O2 Melting Point 81ºC
MSDS N/A Flash Point 150.3ºC

 Names

Name ethyl 6-chloro-5-cyano-2-(trifluoromethyl)pyridine-3-carboxylate

 Chemical & Physical Properties

Density 1.47g/cm3
Boiling Point 325ºC at 760mmHg
Melting Point 81ºC
Molecular Formula C10H6ClF3N2O2
Molecular Weight 278.61500
Flash Point 150.3ºC
Exact Mass 278.00700
PSA 62.98000
LogP 2.80218
Vapour Pressure 0.0158mmHg at 25°C
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 20/21/22
Safety Phrases 23-36/37/39
HS Code 2933399090

 Synthetic Route

~92%

Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate Structure

Ethyl 2-chloro-...

CAS#:175277-73-3

Literature: ASTRAZENECA AB Patent: WO2008/4943 A1, 2008 ; Location in patent: Page/Page column 54-55 ; WO 2008/004943 A1

~%

Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate Structure

Ethyl 2-chloro-...

CAS#:175277-73-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2877 - 2881

~%

Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate Structure

Ethyl 2-chloro-...

CAS#:175277-73-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2877 - 2881

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%