D-(+)-Galactosamine hydrochloride

Modify Date: 2024-01-02 17:51:26

D-(+)-Galactosamine hydrochloride Structure
D-(+)-Galactosamine hydrochloride structure
 Common Name D-(+)-Galactosamine hydrochloride
CAS Number 1772-03-8 Molecular Weight 215.63
Density N/A Boiling Point 532.5ºC at 760 mmHg
Molecular Formula C6H14ClNO5 Melting Point 182-185 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 275.8ºC

 Use of D-(+)-Galactosamine hydrochloride


D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2].

 Names

Name D(+)-Galactosamine hydrochloride
Synonym More Synonyms

 D-(+)-Galactosamine hydrochloride Biological Activity

Description D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2].
Related Catalog
References

[1]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770.

[2]. Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice. Biochem Biophys Rep. 2017;12:166-171. Published 2017 Oct 13.

 Chemical & Physical Properties

Boiling Point 532.5ºC at 760 mmHg
Melting Point 182-185 °C (dec.)(lit.)
Molecular Formula C6H14ClNO5
Molecular Weight 215.63
Flash Point 275.8ºC
Exact Mass 215.056046
PSA 116.17000
Vapour Pressure 5.53E-10mmHg at 25°C
Index of Refraction 96 ° (C=1, H2O)
Storage condition 2~8°C
Water Solubility SOLUBLE

 MSDS

Name: d-(+)-Galactosamine Hydrochloride 99% Material Safety Data Sheet
Synonym: Chondrosamine hydrochloride; 2-Amino-2-deoxy-D-galactose hydrochlorid
CAS: 1772-03-8
Section 1 - Chemical Product MSDS Name:d-(+)-Galactosamine Hydrochloride 99% Material Safety Data Sheet
Synonym:Chondrosamine hydrochloride; 2-Amino-2-deoxy-D-galactose hydrochlorid
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1772-03-8 D-(+)-Galactosamine hydrochloride 99 217-198-1
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1772-03-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 178 - 190 deg C (dec.)
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 190 deg C
Solubility in water: soluble in water
Specific Gravity/Density:
Molecular Formula: C6H13NO5.HCl
Molecular Weight: 215.64
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chloride fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1772-03-8: LW5500000 LD50/LC50:
Not available.
Carcinogenicity:
D-(+)-Galactosamine hydrochloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 1772-03-8: No information available.
Canada
CAS# 1772-03-8 is listed on Canada's NDSL List.
CAS# 1772-03-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1772-03-8 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LW5500000
HS Code 2922399090

 Customs

HS Code 2922399090
Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

More Articles
An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.

Genes Immun. 15(5) , 320-32, (2014)

Genetic and immunological analysis of host-pathogen interactions can reveal fundamental mechanisms of susceptibility and resistance to infection. Modeling human infectious diseases among inbred mouse ...

Towards a full integration of optimization and validation phases: An analytical-quality-by-design approach

J. Chromatogr. A. 1395 , 88-98, (2015)

• An enhanced quality-by-design strategy throughout the analytical method lifecycle. • Quantitative design space: an innovative approach for development of analytical methods. • Integrated approaches ...

Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.

Leukemia 29(1) , 145-56, (2015)

The systemic inflammatory response observed during acute graft-versus-host disease (aGVHD) is driven by proinflammatory cytokines, a 'cytokine storm'. The function of plasmin in regulating the inflamm...

 Synonyms

Galactosamine
2-Amino-2-deoxy-D-galactopyranose hydrochloride D-Chondrosamine hydrochloride
D-GalactosaMine HC1
2-deoxy-2-amino-D-galactose hydrochloride
α-D-Galactopyranose, 2-amino-2-deoxy-, hydrochloride (1:1)
GALACTOSAMINE HCL
2-aMino-2-deoxy-L-idose
D-GALN HCL
D-(+)-Galactosamine hydrochloride
2-Amino-2-deoxy-D-galactopyranose hydrochloride,D-Chondrosamine hydrochloride
2-amino-2-deoxy-D-galactopyranose hydrochloride
Chondrosamine Hydrochloride
2-Amino-2-deoxy-α-D-galactopyranose hydrochloride (1:1)
D-GALACTOSAMINE HCL
CHONDROSAMINE
EINECS 217-198-1
MFCD00135830
(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
D-CHONDROSAMINE HCL
GALACTOSAMINE HCL,D
N-Acetylgalactosamine hydrochloride
Top Suppliers:I want be here

Get all suppliers and price by the below link:

D-(+)-Galactosamine hydrochloride suppliers

Price: ￥62/1g

Reference only. check more D-(+)-Galactosamine hydrochloride price

Related Compounds: More...
D(+)-Galactosamine-13C hydrochloride
478518-54-6
GalN-HCl-β-DMT
1415305-18-8
2-amino-3,4,5,6-tetrahydroxy-hexanal
25591-10-0
D-(+)-Norephedrine hydrochloride
40626-29-7
D-(+)-Vesamicol hydrochloride
112709-60-1
D-(+)-Carnitine hydrochloride
10017-44-4
D(+)-A-HYDRAZINOHISTIDINE HYDROCHLORIDE
1199-91-3
D(+)-Pipecolinic acid hydrochloride
38470-14-3
D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride
141109-19-5
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
Phenol, 2-[4-[(3S)-3-pyrrolidinylamino]-2-quinazolinyl]-
1146159-38-7
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
849349-65-1
Chemsrc provides D-(+)-Galactosamine hydrochloride(CAS#:1772-03-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of D-(+)-Galactosamine hydrochloride are included as well.>> amp version: D-(+)-Galactosamine hydrochloride

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved