D-(3,3,3-2H3)Alanine

Modify Date: 2024-01-10 07:38:00

D-(3,3,3-2H3)Alanine structure	Common Name	D-(3,3,3-2H3)Alanine
	CAS Number	177614-69-6	Molecular Weight	92.112
	Density	1.2±0.1 g/cm3	Boiling Point	212.9±23.0 °C at 760 mmHg
	Molecular Formula	C₃H₄D₃NO₂	Melting Point	291ºC (dec.)(lit.)
	MSDS	USA	Flash Point	82.6±22.6 °C

Use of D-(3,3,3-2H3)Alanine

D-Alanine-d3 ((R)-Alanine-d3) is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

Name	d-alanine-3,3,3-d3
Synonym	More Synonyms

Description	D-Alanine-d3 ((R)-Alanine-d3) is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27. [3]. Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70.

Density	1.2±0.1 g/cm3
Boiling Point	212.9±23.0 °C at 760 mmHg
Melting Point	291ºC (dec.)(lit.)
Molecular Formula	C₃H₄D₃NO₂
Molecular Weight	92.112
Flash Point	82.6±22.6 °C
Exact Mass	92.066505
PSA	63.32000
LogP	-0.68
Vapour Pressure	0.1±0.9 mmHg at 25°C
Index of Refraction	1.460

Precursor 0
DownStream 1
CAS#:177614-70-9 N-(tert-Butoxyc...

D-Alanine-3,3,3-d

D-(3,3,3-H)Alanine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: D-Alanine-3,3,3-d3
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

D-(3,3,3-2H3)Alanine suppliers

D-(3,3,3-2H3)Alanine price