BP-5-087

Modify Date: 2024-08-12 20:21:52

BP-5-087 Structure
BP-5-087 structure
Common Name BP-5-087
CAS Number 1803281-30-2 Molecular Weight 770.691
Density N/A Boiling Point N/A
Molecular Formula C36H30F8N2O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BP-5-087


A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.

 Names

Name BP-5-087

 BP-5-087 Biological Activity

Description A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.
References References 1. Eiring AM, et al. Leukemia. 2015 Mar;29(3):586-597. 2. Eiring AM, et al. Leuk Suppl. 2014 Dec;3(Suppl 1):S5-6. View Related Products by Target STAT

 Chemical & Physical Properties

Molecular Formula C36H30F8N2O6S
Molecular Weight 770.691
Top Suppliers:I want be here



Get all suppliers and price by the below link:

BP-5-087 suppliers

BP-5-087 price