17β-Estradiol 17β-D-Glucuronide

Modify Date: 2024-01-08 12:19:49

17β-Estradiol 17β-D-Glucuronide Structure
17β-Estradiol 17β-D-Glucuronide structure
Common Name 17β-Estradiol 17β-D-Glucuronide
CAS Number 1806-98-0 Molecular Weight 448.51
Density N/A Boiling Point N/A
Molecular Formula C24H32O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 17β-Estradiol 17β-D-Glucuronide


Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter[1].

 Names

Name 17β-estradiol 17-glucosiduronic acid
Synonym More Synonyms

 17β-Estradiol 17β-D-Glucuronide Biological Activity

Description Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter[1].
Related Catalog
References

[1]. Kinbara S, et al. Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats. Scand J Gastroenterol. 1997;32(9):947-952.  

[2]. Kanai N,et al. Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am J Physiol. 1996 Feb;270(2 Pt 2):F326-31.  

 Chemical & Physical Properties

Molecular Formula C24H32O8
Molecular Weight 448.51
Exact Mass 448.21000
PSA 136.68000
LogP 1.52570
Vapour Pressure 2.34E-20mmHg at 25°C

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

17β-Estradiol 17β-D-Glucuronide
[14C]-Estradiol 17beta-glucuronide
17beta-estradiol 17-glucosiduronic acid
1,3,5(10)-ESTRATRIEN-17ALPHA-ETHYNYL-3,17BETA-DIOL-17BETA-GLUCURONIDE
17Beta-Estradiol 17Beta-D-Glucuronide