Contezolid acefosamil

Modify Date: 2024-01-03 17:49:48

Contezolid acefosamil Structure
Contezolid acefosamil structure
Common Name Contezolid acefosamil
CAS Number 1807497-11-5 Molecular Weight 530.348
Density 1.6±0.1 g/cm3 Boiling Point 703.1±70.0 °C at 760 mmHg
Molecular Formula C20H18F3N4O8P Melting Point N/A
MSDS N/A Flash Point 379.0±35.7 °C

 Use of Contezolid acefosamil


Contezolid acefosamil (MRX-4) is the orally active prodrug of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA

 Names

Name Acetyl hydrogen 1,2-oxazol-3-yl({(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-3,4-dihydro-1(2H)-pyridinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)phosphoramidate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 703.1±70.0 °C at 760 mmHg
Molecular Formula C20H18F3N4O8P
Molecular Weight 530.348
Flash Point 379.0±35.7 °C
Exact Mass 530.081421
LogP -1.66
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.600

 Synonyms

Phosphoramidic acid, N-[[(5R)-3-[4-(3,4-dihydro-4-oxo-1(2H)-pyridinyl)-2,3,5-trifluorophenyl]-2-oxo-5-oxazolidinyl]methyl]-N-3-isoxazolyl-, monoacetyl ester
Acetyl hydrogen 1,2-oxazol-3-yl({(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-3,4-dihydro-1(2H)-pyridinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)phosphoramidate