Pi3kd/v-in-01

Modify Date: 2024-02-24 13:49:26

Pi3kd/v-in-01 Structure
Pi3kd/v-in-01 structure
Common Name Pi3kd/v-in-01
CAS Number 1807551-44-5 Molecular Weight 494.03
Density N/A Boiling Point N/A
Molecular Formula C21H24ClN5O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pi3kd/v-in-01


PI3KD/V-IN-01 is a potent ATP-competitive PI3Kδ/Vps34 dual inhibitor.

 Names

Name PI3KD/V-IN-01

 Pi3kd/v-in-01 Biological Activity

Description PI3KD/V-IN-01 is a potent ATP-competitive PI3Kδ/Vps34 dual inhibitor.
References 1. Liu X, Wang A, Liang X, Liu J, Zou F, Chen C, Zhao Z, Deng Y, Wu H, Qi Z, Wang B, Wang L, Liu F, Xu Y, Wang W, Fernandes SM, Stone RM, Galinsky IA, Brown JR, Loh T, Griffin JD, Zhang S, Weisberg EL, Zhang X, Liu J, Liu Q. Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies. Oncotarget. 2016 Aug 16;7(33):53515-53525. doi: 10.18632/oncotarget.10650. PubMed PMID: 27447747; PubMed Central PMCID: PMC5288202.

 Chemical & Physical Properties

Molecular Formula C21H24ClN5O3S2
Molecular Weight 494.03