Poloxin-2
Modify Date: 2024-07-17 18:58:53
Poloxin-2 structure
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Common Name | Poloxin-2 | ||
|---|---|---|---|---|
| CAS Number | 1807690-39-6 | Molecular Weight | 269.3 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H15NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Poloxin-2A potent, selective PLK1 PBD inhibitor with IC50 of 1.36 uM; shows >10-fold selectivity over Plk2 PBD and Plk3 PBD; significantly improved potency and selectivity over Poloxin; induces mitotic arrest and apoptosis in cultured human tumor cells at low micromolar concentrations. |
| Name | Poloxin-2 |
|---|
| Description | A potent, selective PLK1 PBD inhibitor with IC50 of 1.36 uM; shows >10-fold selectivity over Plk2 PBD and Plk3 PBD; significantly improved potency and selectivity over Poloxin; induces mitotic arrest and apoptosis in cultured human tumor cells at low micromolar concentrations. |
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| References | References 1. Scharow A, et al. ACS Chem Biol. 2015 Nov 20;10(11):2570-9. 2. Scharow A, et al. Chembiochem. 2016 Apr 15;17(8):759-67. View Related Products by Target Polo-like Kinase (PLK) |
| Molecular Formula | C16H15NO3 |
|---|---|
| Molecular Weight | 269.3 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Poloxin-2
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Poloxin-2
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Poloxin-2
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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