MM-206
Modify Date: 2024-01-13 06:59:28
MM-206 structure
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Common Name | MM-206 | ||
|---|---|---|---|---|
| CAS Number | 1809581-87-0 | Molecular Weight | 497.458 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 601.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C22H12F5NO3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 317.8±34.3 °C | |
Use of MM-206A novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD); also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM, |
| Name | MM 206 |
|---|---|
| Synonym | More Synonyms |
| Description | A novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD); also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM, |
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| References | References 1. Minus MB, et al. Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13085-9. View Related Products by Target STAT |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 601.9±65.0 °C at 760 mmHg |
| Molecular Formula | C22H12F5NO3S2 |
| Molecular Weight | 497.458 |
| Flash Point | 317.8±34.3 °C |
| Exact Mass | 497.017883 |
| LogP | 5.81 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.694 |
| MFCD30179936 |
| Benzenesulfonamide, 2,3,4,5,6-pentafluoro-N-[4-hydroxy-3-(phenylthio)-1-naphthalenyl]- |
| 2,3,4,5,6-Pentafluoro-N-(4-hydroxy-3-(phenylthio)naphthalen-1-yl)benzenesulfonamide |
| 2,3,4,5,6-Pentafluoro-N-[4-hydroxy-3-(phenylsulfanyl)-1-naphthyl]benzenesulfonamide |
| MM 206 |
| MM-206 |