TAK-071

Modify Date: 2024-01-11 11:13:01

TAK-071 Structure
TAK-071 structure
Common Name TAK-071
CAS Number 1820812-16-5 Molecular Weight 421.46
Density N/A Boiling Point N/A
Molecular Formula C24H24FN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAK-071


TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].

 Names

Name TAK-071

 TAK-071 Biological Activity

Description TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].
Related Catalog
Target

EC50: 520 nM (M1R)[1]

References

[1]. Sako Y, et al. TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects. Neuropsychopharmacology. 2018 Aug 1. doi: 10.1038/s41386-018-0168-8.

 Chemical & Physical Properties

Molecular Formula C24H24FN3O3
Molecular Weight 421.46
Storage condition 2-8℃