2-bromohexadecanoic acid structure
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Common Name | 2-bromohexadecanoic acid | ||
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CAS Number | 18263-25-7 | Molecular Weight | 335.32 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 403.4±18.0 °C at 760 mmHg | |
Molecular Formula | C16H31BrO2 | Melting Point | 52-54 °C | |
MSDS | Chinese USA | Flash Point | 197.8±21.2 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of 2-bromohexadecanoic acid2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. |
Name | 2-bromohexadecanoic acid |
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Synonym | More Synonyms |
Description | 2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. |
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Related Catalog | |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 403.4±18.0 °C at 760 mmHg |
Melting Point | 52-54 °C |
Molecular Formula | C16H31BrO2 |
Molecular Weight | 335.32 |
Flash Point | 197.8±21.2 °C |
Exact Mass | 334.150726 |
PSA | 37.30000 |
LogP | 7.76 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.480 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2915900090 |
~% 2-bromohexadeca... CAS#:18263-25-7 |
Literature: Journal of the Chemical Society, , vol. 87, p. 1901 Chemische Berichte, , vol. 25, p. 486 Chemische Berichte, , vol. 24, p. 939 |
~% 2-bromohexadeca... CAS#:18263-25-7 |
Literature: Yakugaku Zasshi, , vol. 61, p. 406;dtsch.Ref.S.127 Chem.Abstr., , p. 9356 |
Precursor 2 | |
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DownStream 10 | |
HS Code | 2915900090 |
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Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
Local palmitoylation cycles define activity-regulated postsynaptic subdomains.
J. Cell Biol. 202(1) , 145-61, (2013) Distinct PSD-95 clusters are primary landmarks of postsynaptic densities (PSDs), which are specialized membrane regions for synapses. However, the mechanism that defines the locations of PSD-95 cluste... |
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Estrogen receptor-alpha 36 mediates the anti-apoptotic effect of estradiol in triple negative breast cancer cells via a membrane-associated mechanism.
Biochim. Biophys. Acta 1843(11) , 2796-806, (2014) 17β-Estradiol can promote the growth and development of several estrogen receptor (ER)-negative breast cancers. The effects are rapid and non-genomic, suggesting that a membrane-associated ER is invol... |
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Identification of G protein alpha subunit-palmitoylating enzyme.
Mol. Cell. Biol. 29(2) , 435-47, (2009) The heterotrimeric G protein alpha subunit (Galpha) is targeted to the cytoplasmic face of the plasma membrane through reversible lipid palmitoylation and relays signals from G-protein-coupled recepto... |
Hexadecanoic acid, 2-bromo- |
2-bromopalmitate |
2-Bromopalmitic acid |
UNII:7EI4G5X28Z |
2-bromopalmitate,(+-)-isomer |
2-bromo-hexadecanoic acid |
Hexadecanoic acid,2-bromo |
EINECS 242-137-0 |
MFCD00004215 |
bromopalmitic acid |
2-Bromohexadecanoic acid |