L-Homocystine-d8

Modify Date: 2024-01-17 12:01:12

L-Homocystine-d8 structure	Common Name	L-Homocystine-d8
	CAS Number	182755-41-5	Molecular Weight	276.40
	Density	1.4±0.1 g/cm3	Boiling Point	507.6±50.0 °C at 760 mmHg
	Molecular Formula	C₈H₈D₈N₂O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	260.8±30.1 °C

Use of L-Homocystine-d8

L-Homocystine-d8 is the deuterium labeled L-Homocystine. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

Name	(2S)-2-(2H2)Amino-4-{[3-amino-3-carboxy(1-2H1)propyl]disulfanyl}(2H5)butanoic acid
Synonym	More Synonyms

Description	L-Homocystine-d8 is the deuterium labeled L-Homocystine. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Padmanabhan R, et al. Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos. Eur J Nutr. 2006 Sep;45(6):311-9

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Padmanabhan R, et al. Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos. Eur J Nutr. 2006 Sep;45(6):311-9

Density	1.4±0.1 g/cm3
Boiling Point	507.6±50.0 °C at 760 mmHg
Molecular Formula	C₈H₈D₈N₂O₄S₂
Molecular Weight	276.40
Flash Point	260.8±30.1 °C
Exact Mass	276.105347
LogP	1.03
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.619

(2S)-2-(H)Amino-4-{[3-amino-3-carboxy(1-H)propyl]disulfanyl}(H)butanoic acid

Butanoic-2,3,3,4,4-d acid, 2-(amino-d)-4-[(3-amino-3-carboxypropyl-1-d)dithio]-, (2S)-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: L-Homocystine-3,3,3’,3’,4,4,4’,4’-d8
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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