4-Methylumbelliferyl Oleate
4-Methylumbelliferyl Oleate structure
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Common Name | 4-Methylumbelliferyl Oleate | ||
|---|---|---|---|---|
| CAS Number | 18323-58-5 | Molecular Weight | 440.61500 | |
| Density | 1.023g/cm3 | Boiling Point | 571.5ºC at 760mmHg | |
| Molecular Formula | C28H40O4 | Melting Point | 37-38ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 281.3ºC | |
Use of 4-Methylumbelliferyl Oleate4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm)[1][2]. |
| Name | 4-methylumbelliferyl oleate |
|---|---|
| Synonym | More Synonyms |
| Description | 4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm)[1][2]. |
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| Related Catalog | |
| In Vitro | The inhibitory activity against pancreatic lipase was measured using 4-Methylumbelliferyl (4-MU) oleate as a substrate. The reaction mixture consisted of 50 µL 0.1 mM 4-MU oleate, 20 µL McIlvane buffer (0.1 M citrate-Na2 HPO4, pH 7.4), and 5 µL of sample solution. Porcine pancreatic lipase (25 µL) was added to the reaction mixture and the final volume was adjusted to 0.1 ml. After the mixture was incubated at 37℃ for 10 min, the amount of 4-MU released by the lipase was measured using a fluorescence multi-detection reader at an excitation wavelength of 320 nm and an emission wavelength of 450 nm[1]. |
| References |
| Density | 1.023g/cm3 |
|---|---|
| Boiling Point | 571.5ºC at 760mmHg |
| Melting Point | 37-38ºC(lit.) |
| Molecular Formula | C28H40O4 |
| Molecular Weight | 440.61500 |
| Flash Point | 281.3ºC |
| Exact Mass | 440.29300 |
| PSA | 56.51000 |
| LogP | 8.04430 |
| Vapour Pressure | 4.53E-13mmHg at 25°C |
| Index of Refraction | 1.515 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932209090 |
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~95%
4-Methylumbelli... CAS#:18323-58-5 |
| Literature: Kidwai, Mazaahir; Poddar, Vaishali; Poddar, Roona Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 5 p. 715 - 720 |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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