GLS1 Inhibitor

Modify Date: 2024-01-10 19:39:05

GLS1 Inhibitor Structure
GLS1 Inhibitor structure
Common Name GLS1 Inhibitor
CAS Number 1832646-52-2 Molecular Weight 411.5
Density N/A Boiling Point N/A
Molecular Formula C19H21N7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GLS1 Inhibitor


GLS1 inhibitor is an inhibitor of glutaminase 1

 Names

Name GLS1 Inhibitor

 GLS1 Inhibitor Biological Activity

Description GLS1 inhibitor is an inhibitor of glutaminase 1
In Vitro GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50 = 0.021 μM).1 It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model.

 Chemical & Physical Properties

Molecular Formula C19H21N7O2S
Molecular Weight 411.5
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