DH-376
Modify Date: 2024-04-11 10:00:02
DH-376 structure
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Common Name | DH-376 | ||
|---|---|---|---|---|
| CAS Number | 1848233-57-7 | Molecular Weight | 542.587 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H28F2N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DH-376DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively; shows excellent selectivity for DAGLs with the only detectable serine hydrolase off-targets being ABHD6 (pIC50=7.0) and PLA2G7; significantly decreases whole brain levels of 2-AG, anandamide, and arachidonic acid in the mouse LPS inflammatory pain model. |
| Name | DH-376 |
|---|
| Description | DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively; shows excellent selectivity for DAGLs with the only detectable serine hydrolase off-targets being ABHD6 (pIC50=7.0) and PLA2G7; significantly decreases whole brain levels of 2-AG, anandamide, and arachidonic acid in the mouse LPS inflammatory pain model. |
|---|---|
| References | References 1. Ogasawara D, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):26-33. View Related Products by Target Diacylglycerol Lipase (DAGL) |
| Molecular Formula | C31H28F2N4O3 |
|---|---|
| Molecular Weight | 542.587 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: DH376
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: DH-376
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: DH-376
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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